Clinical significance of estrogen receptor β in breast and prostate cancer from biological aspects

  title={Clinical significance of estrogen receptor β in breast and prostate cancer from biological aspects},
  author={Yoko Omoto and Hirotaka Iwase},
  booktitle={Cancer science},
Breast and prostate cancers are among the most common of all cancers. They are referred to as hormone-dependent cancers, because estrogen and androgen are involved in their development and growth. The effects of these hormones are mediated by their respective receptors, estrogen receptor (ER) α and androgen receptor. Around 18 years ago, a second ER, ERβ, which has a very similar structure to ERα, was discovered. Its function has been investigated using a variety of methods and biological… CONTINUE READING
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