Clinical significance of elevated osteopontin levels in head and neck cancer patients.

@article{Eto2007ClinicalSO,
  title={Clinical significance of elevated osteopontin levels in head and neck cancer patients.},
  author={Mayumi Eto and Satoru Kodama and Nozomi Nomi and Naoki Uemura and Masashi Suzuki},
  journal={Auris, nasus, larynx},
  year={2007},
  volume={34 3},
  pages={
          343-6
        }
}
OBJECTIVES Osteopontin (OPN) is associated with several human malignancies, but the role of OPN in head and neck cancer (HNC) remains unclear. We investigated the clinicopathologic relevance of serum OPN levels in HNC patients. METHODS Serum OPN levels in HNC patients were determined by quantitative sandwich enzyme immunoassay (EIA). OPN levels and their correlation with clinical features were examined. In addition, serum squamous cell carcinoma (SCC) antigen was examined simultaneously… CONTINUE READING

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