Clinical significance of cellular drug resistance in childhood leukemia.

  title={Clinical significance of cellular drug resistance in childhood leukemia.},
  author={Gertjan J. L. Kaspers and Anjo J. P. Veerman},
  journal={Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer},
Cellular drug resistance is an important determinant of the response to chemotherapy, and its precise measurement may have clinical relevance. Potential applications are: prognostic factor for risk-group stratification, tailored chemotherapy for subgroups or individual patients with a specific cellular drug resistance profile, determination of cross-resistance patterns, study of drug interactions, study of resistance modulation or circumvention, selection of patients for phase II studies and… CONTINUE READING


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