Clinical significance of ST3Gal IV expression in human renal cell carcinoma.

@article{Saito2002ClinicalSO,
  title={Clinical significance of ST3Gal IV expression in human renal cell carcinoma.},
  author={Seiichi Saito and Shin-ichi Yamashita and Mareyuki Endoh and Takashi Yamato and Senji Hoshi and Chikara Ohyama and Ryuji Watanabe and Akihiro Ito and Makoto Satoh and Tadashi Wada and James C Paulson and Yoichi Arai and Taeko Miyagi},
  journal={Oncology reports},
  year={2002},
  volume={9 6},
  pages={1251-5}
}
Alteration of sialyltransferase expression has been implicated in carcinogenesis. Out of sialyltransferases cloned to date, we focused on ST3Gal IV expression in human renal cell carcinoma (RCC). Levels of ST3Gal IV mRNA were examined in human RCC in comparison with non-tumor kidney. ST3Gal IV cDNA obtained by polymerase chain reaction from cDNA library of human RCC cell line ACHN was identical to STZ in nucleotide sequence. Northern blot analysis was performed for 24 non-tumor kidney and 25… CONTINUE READING

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