A monotonic and prognostic genomic signature from fibroblasts for colorectal cancer initiation, progression, and metastasis.
- Mireia Berdiel-Acer, Daniel Cuadras, +8 authors David G Molleví
- Molecular cancer research : MCR
- 2014
Clinical significance of Rho GDP dissociation inhibitor 2 in colorectal carcinoma
- Published 2011 in International Journal of Clinical Oncology
Abstract
Small GTPase proteins, including RhoA, RhoB, RhoC, Rac1, and cdc42, are important molecules for linking cell shape and cell-cycle progression because of their role in both cytoskeletal arrangements and mitogenic signaling. Over-expression of wild-type or constitutively active forms of RhoA has been shown to induce invasive behavior in non-invasive rat… (More)
Topics
- Colorectal Carcinoma
- Adult Fanconi syndrome
- Guanosine Diphosphate
- Neoplasms
- liver metastases
- melanoma
- cancer cell
- Liver carcinoma
- prognostic
- Prognostic Factors
- Mammary Neoplasms
- Bladder Neoplasm
- Guanosine Triphosphate Phosphohydrolases
- Polymerase Chain Reaction
- Inflammatory Breast Carcinoma
- ARHGDIB gene
- Colorectal Cancer
- Mucous Membrane