Clinical significance of MT1-MMP mRNA expression in breast cancer.


Membrane-type 1 matrix metalloproteinase (MT1-MMP) is known as an activator of MMP-2. We reported that the expression of MT1-MMP is a powerful indicator of lymph node metastasis in gastric cancers. We now examined the possibility that MT1-MMP expression also is an indicator of lymph node metastasis in breast cancer. We examined the clinicopathologic… (More)


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