Clinical significance in the change of decline in ALSFRS-R

@article{CastrilloViguera2010ClinicalSI,
  title={Clinical significance in the change of decline in ALSFRS-R},
  author={Carmen Castrillo-Viguera and D. Grasso and E. Simpson and J. Shefner and M. Cudkowicz},
  journal={Amyotrophic Lateral Sclerosis},
  year={2010},
  volume={11},
  pages={178 - 180}
}
  • Carmen Castrillo-Viguera, D. Grasso, +2 authors M. Cudkowicz
  • Published 2010
  • Medicine
  • Amyotrophic Lateral Sclerosis
  • Our objective was to survey ALS clinicians and researchers regarding what percentage reduction in the ALSFRS-R (Amyotrophic Lateral Sclerosis Functional Rating Scale – Revised) slope they would consider clinically meaningful. A nine-question survey was provided to 65 members of the Northeast ALS Consortium (NEALS). They were asked to rate the clinical relevance of 10–50% changes in decline of the ALSFRS-R slope on a seven-point scale (1–7), where 1=‘not at all clinically meaningful’, 4… CONTINUE READING
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