Clinical significance and expression of PUMA, MCL-1, and p53 in human renal cell carcinoma and para-carcinoma tissues.

  title={Clinical significance and expression of PUMA, MCL-1, and p53 in human renal cell carcinoma and para-carcinoma tissues.},
  author={H. Xia and H. Cui and L. Su and Z. Zhang and X. Y. Yang and S. Ning and X. Su},
  journal={Genetics and molecular research : GMR},
  volume={16 3}
  • H. Xia, H. Cui, +4 authors X. Su
  • Published 2017
  • Biology, Medicine
  • Genetics and molecular research : GMR
We investigated the expression level of p53 upregulated modulator of apoptosis (PUMA), myeloid cell leukemia-I (MCL-1), and p53 in renal cell carcinoma (RCC) and para-carcinoma tissues, as well as their clinical significance. The expression levels of PUMA, MCL-1, and p53 in RCC and para-carcinoma tissues were measured using immunohistochemical and quantitative real-time PCR methods. Correlations between protein expression and pathological characteristics were analyzed. Renal clear cell… Expand
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