Clinical sensitivity of HPV assays for the detection of high grade cervical disease in cervical samples treated with glacial acetic acid.

@article{Moore2016ClinicalSO,
  title={Clinical sensitivity of HPV assays for the detection of high grade cervical disease in cervical samples treated with glacial acetic acid.},
  author={Catherine Moore and Edward Duvall and Ellen Braby and Graham Reid and Eileen Docherty and Logan Grieve and Heather Ann Cubie and Cat Graham and Kate Cuschieri},
  journal={Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology},
  year={2016},
  volume={79},
  pages={32-35}
}
BACKGROUND Lysis of bloody liquid based cytology (LBC) specimens with glacial acetic acid (GAA) is performed to aid cytological interpretation. However, the influence of GAA treatment on HPV detection is not fully understood and in studies designed to assess this, few cases of high-grade disease have been included. OBJECTIVES To assess the sensitivity of HPV molecular tests for the detection of high grade cervical disease in GAA treated samples STUDY DESIGN A total of 207 specimens… CONTINUE READING