Clinical safety and tolerance of mitoxantrone.

  title={Clinical safety and tolerance of mitoxantrone.},
  author={Robert Crossley},
  journal={Seminars in oncology},
  volume={11 3 Suppl 1},
Mitoxantrone has been administered to more than 4000 patients worldwide. From this data base, a summary of the latest information is presented on the effect of mitoxantrone on bone marrow, on its nonmyelosuppressive acute toxicities, on its local tolerability, and on measurements of organ function. Most of these patients had solid tumors and were treated… CONTINUE READING