Clinical roles of increased populations of Foxp3+CD4+ T cells in peripheral blood from advanced pancreatic cancer patients.

@article{Ikemoto2006ClinicalRO,
  title={Clinical roles of increased populations of Foxp3+CD4+ T cells in peripheral blood from advanced pancreatic cancer patients.},
  author={Tetsuya Ikemoto and Takeshi Yamaguchi and Yuji Morine and Satoru Imura and Yuji Soejima and Masahiko Fujii and Yoichi Maekawa and Koji Yasutomo and Mitsuo Shimada},
  journal={Pancreas},
  year={2006},
  volume={33 4},
  pages={386-90}
}
OBJECTIVES Further metastasis should be avoided in pancreatic cancer (PC) patients for effective surgical treatment. Regulatory T cells (Foxp3CD4 T cells including CD4CD25 T cells and CD4CD25 T cells) play important roles in tumor immunity. This study aimed to investigate whether regulatory T cells participate in metastasis. METHODS Peripheral blood was withdrawn from PC patients, as well as healthy volunteer donors as controls. The peripheral blood mononuclear cells (PBMCs) were subjected to… CONTINUE READING

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