Clinical role of diosmectite in the management of diarrhea

  title={Clinical role of diosmectite in the management of diarrhea},
  author={A. Guarino and A. Vecchio and M. R. Pirozzi},
  journal={Expert Opinion on Drug Metabolism & Toxicology},
  pages={433 - 440}
  • A. Guarino, A. Vecchio, M. R. Pirozzi
  • Published 2009
  • Medicine
  • Expert Opinion on Drug Metabolism & Toxicology
  • Background: Diosmectite (DS), an antidiarrheal absorbent natural clay, was proposed for treatment of acute gastroenteritis and more recently considered for diarrhea within the functional bowel disorder syndrome. Objective: To review pharmacology efficacy, mechanisms of action and safety of DS. Methods: We consulted PubMed/Medline using the keywords of smectite and diarrhea or gastroenteritis, and reviewed most recent recommendations by scientific societies. Conclusions: Solid data show that DS… CONTINUE READING


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