Clinical role of diosmectite in the management of diarrhea

@article{Guarino2009ClinicalRO,
  title={Clinical role of diosmectite in the management of diarrhea},
  author={A. Guarino and A. Vecchio and M. R. Pirozzi},
  journal={Expert Opinion on Drug Metabolism & Toxicology},
  year={2009},
  volume={5},
  pages={433 - 440}
}
  • A. Guarino, A. Vecchio, M. R. Pirozzi
  • Published 2009
  • Medicine
  • Expert Opinion on Drug Metabolism & Toxicology
  • Background: Diosmectite (DS), an antidiarrheal absorbent natural clay, was proposed for treatment of acute gastroenteritis and more recently considered for diarrhea within the functional bowel disorder syndrome. Objective: To review pharmacology efficacy, mechanisms of action and safety of DS. Methods: We consulted PubMed/Medline using the keywords of smectite and diarrhea or gastroenteritis, and reviewed most recent recommendations by scientific societies. Conclusions: Solid data show that DS… CONTINUE READING

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 54 REFERENCES
    Managing acute gastroenteritis among children: oral rehydration, maintenance, and nutritional therapy.
    • 530
    • Highly Influential
    • PDF
    Childhood functional gastrointestinal disorders: child/adolescent.
    • 1,412
    • PDF
    Racecadotril in the treatment of acute watery diarrhea in children.
    • 223
    • PDF
    Efficacy and tolerability of racecadotril in acute diarrhea in children.
    • 109
    Loperamide Therapy for Acute Diarrhea in Children: Systematic Review and Meta-Analysis
    • 114
    • PDF
    Anti‐inflammatory effect of diosmectite in hapten‐induced colitis in the rat
    • 73
    • PDF