Clinical role of diosmectite in the management of diarrhea

  title={Clinical role of diosmectite in the management of diarrhea},
  author={Alfredo Guarino and Andrea Lo Vecchio and Maria Rosaria Pirozzi},
  journal={Expert Opinion on Drug Metabolism \& Toxicology},
  pages={433 - 440}
Background: Diosmectite (DS), an antidiarrheal absorbent natural clay, was proposed for treatment of acute gastroenteritis and more recently considered for diarrhea within the functional bowel disorder syndrome. Objective: To review pharmacology efficacy, mechanisms of action and safety of DS. Methods: We consulted PubMed/Medline using the keywords of smectite and diarrhea or gastroenteritis, and reviewed most recent recommendations by scientific societies. Conclusions: Solid data show that DS… Expand
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The effects of dietary supplementation of palygorskite on intestinal integrity in weaned piglets were investigated in this study. Pigs weaned at 24 days of age (n = 27) were allocated to three groupsExpand
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  • 2004
Dioctahedral smectite appeared in this study to be an effective and safe treatment of chronic functional diarrhoea, its effect starting during the first week of treatment and consisting in a decrease in the frequency of daily bowel movements and improvement of stool consistency. Expand
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