Clinical review: The pathogenetic role of cortisol in the metabolic syndrome: a hypothesis.
@article{Anagnostis2009ClinicalRT, title={Clinical review: The pathogenetic role of cortisol in the metabolic syndrome: a hypothesis.}, author={P. Anagnostis and V. Athyros and K. Tziomalos and A. Karagiannis and D. Mikhailidis}, journal={The Journal of clinical endocrinology and metabolism}, year={2009}, volume={94 8}, pages={ 2692-701 } }
CONTEXT
The metabolic syndrome (MetS) is a cluster of metabolic abnormalities that increase the risk for type 2 diabetes mellitus and vascular disease. The common characteristics of MetS and hypercortisolemic conditions such as Cushing's syndrome (CS) suggest that the pathogenesis of MetS and central obesity might involve prolonged and excessive exposure to glucocorticoids. The present review summarizes the evidence on the potential role of cortisol in the pathogenesis of MetS and discusses new… CONTINUE READING
Paper Mentions
Interventional Clinical Trial
Background:
- Metabolic syndrome is a name given to a group of factors that tend to occur together.
These risk factors include central obesity (extra weight around the… Expand
Conditions | Diabetes, Endocrine Disease |
---|---|
Intervention | Drug |
525 Citations
Cortisol: the villain in metabolic syndrome?
- Medicine
- Revista da Associacao Medica Brasileira
- 2014
- 27
- PDF
Role of testosterone and cortisol in metabolic syndrome and type 2 diabetes mellitus
- Medicine
- 2010
- 2
- PDF
Associations of salivary cortisol levels with metabolic syndrome and its components: the multi-ethnic study of atherosclerosis.
- Medicine
- The Journal of clinical endocrinology and metabolism
- 2011
- 38
- PDF
Secondary metabolic syndrome: the frequency of factors which may underlie the parameters of metabolic syndrome
- Medicine
- Annals of Saudi medicine
- 2013
Subclinical hypercortisolism: a state, a syndrome, or a disease?
- Medicine
- European journal of endocrinology
- 2015
- 85
- PDF
11β‐Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus
- Medicine
- Diabetes, obesity & metabolism
- 2012
- 83
The Role of Cortisol in the Pathogenesis of the Metabolic Syndrome
- Medicine
- Diabetes & metabolism journal
- 2012
- 9
- PDF
Developmental origins of the metabolic syndrome: Body clocks and stress responses
- Biology, Medicine
- Brain, Behavior, and Immunity
- 2011
- 44
References
SHOWING 1-10 OF 146 REFERENCES
Cortisol—cause and cure for metabolic syndrome?
- Medicine
- Diabetic medicine : a journal of the British Diabetic Association
- 2006
- 176
- Highly Influential
Hypothalamic Origin of the Metabolic Syndrome X
- Biology, Medicine
- Annals of the New York Academy of Sciences
- 1999
- 204
Role of glucocorticoids and fatty acids in the impairment of lipid metabolism observed in the metabolic syndrome.
- Medicine
- International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity
- 1995
- 87
The Hypothalamic‐Pituitary‐Adrenal Axis Activity in Obesity and the Metabolic Syndrome
- Biology, Medicine
- Annals of the New York Academy of Sciences
- 2006
- 280
Adrenocortical, Autonomic, and Inflammatory Causes of the Metabolic Syndrome: Nested Case-Control Study
- Medicine
- Circulation
- 2002
- 509
- PDF
The Prevalence of Metabolic Syndrome in Various Populations
- Medicine
- The American journal of the medical sciences
- 2007
- 194
Elevated plasma endothelin as an additional cardiovascular risk factor in patients with Cushing's syndrome.
- Medicine
- European journal of endocrinology
- 2003
- 51
- PDF
Elevated serum uric acid levels in metabolic syndrome: an active component or an innocent bystander?
- Medicine
- Metabolism: clinical and experimental
- 2006
- 227
Activity of the hypothalamic–pituitary–adrenal axis in different obesity phenotypes
- Medicine
- International Journal of Obesity
- 2000
- 121
- PDF