• DOI:10.1042/CS20050161
Corpus ID: 9507693

Clinical relevance of the neurotrophins and their receptors.

@article{Allen2006ClinicalRO,
  title={Clinical relevance of the neurotrophins and their receptors.},
  author={S. Allen and D. Dawbarn},
  journal={Clinical science},
  year={2006},
  volume={110 2},
  pages={
          175-91
        }
}

S. Allen, D. Dawbarn

Published 2006

Medicine

Clinical science

The neurotrophins are growth factors required by discrete neuronal cell types for survival and maintenance, with a broad range of activities in the central and peripheral nervous system in the developing and adult mammal. This review examines their role in diverse disease states, including Alzheimer's disease, depression, pain and asthma. In addition, the role of BDNF (brain-derived neurotrophic factor) in synaptic plasticity and memory formation is discussed. Unlike the other neurotrophins… CONTINUE READING

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