Clinical relevance of the TLR4 11367 polymorphism in patients with major trauma.

@article{Duan2009ClinicalRO,
  title={Clinical relevance of the TLR4 11367 polymorphism in patients with major trauma.},
  author={Zhao-xia Duan and Wei Gu and Lian-yang Zhang and Ding-yuan Du and Ping Hu and J Huang and Q Liu and Zheng-Guo Wang and Jiang Hao and Jianxin Jiang},
  journal={Archives of surgery},
  year={2009},
  volume={144 12},
  pages={1144-8}
}
OBJECTIVE To investigate the clinical relevance of the TLR4 11367 polymorphism in patients with major trauma. DESIGN Genetic functional and association study. SETTING Daping Hospital and Chongqing Emergency Medical Center, Chongqing, China. PATIENTS A total of 132 patients with major trauma were prospectively recruited. MAIN OUTCOME MEASURES The TLR4 11367 polymorphism was genotyped using single-tube, bidirectional, allele-specific amplification method. Whole peripheral blood samples… CONTINUE READING

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