Clinical relevance of circulating cell-free microRNAs in cancer

@article{Schwarzenbach2014ClinicalRO,
  title={Clinical relevance of circulating cell-free microRNAs in cancer},
  author={Heidi Schwarzenbach and Naohiro Nishida and George A. Calin and Klaus Pantel},
  journal={Nature Reviews Clinical Oncology},
  year={2014},
  volume={11},
  pages={145-156}
}
Efficient patient management relies on early diagnosis of disease and monitoring of treatment. In this regard, much effort has been made to find informative, blood-based biomarkers for patients with cancer. Owing to their attributes—which are specifically modulated by the tumour—circulating cell-free microRNAs found in the peripheral blood of patients with cancer may provide insights into the biology of the tumour and the effects of therapeutic interventions. Moreover, the role of microRNAs in… CONTINUE READING

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