Clinical profile and HLA-DRB1 genotype of late onset multiple sclerosis in Western Australia.

@article{Qiu2010ClinicalPA,
  title={Clinical profile and HLA-DRB1 genotype of late onset multiple sclerosis in Western Australia.},
  author={Wei Qiu and Jing-Shan Wu and Alison S L Castley and Ian M James and Joyce Pauline Joseph and Frank T. Christiansen and William M. Carroll and Francis L Mastaglia and Allan G. Kermode},
  journal={Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia},
  year={2010},
  volume={17 8},
  pages={1009-13}
}
We aimed to characterize the clinical profile and human leukocyte antigen (HLA)-DRB1 genotype of patients with late onset multiple sclerosis (LOMS) in Western Australia. The clinical features, laboratory studies and HLA-DRB1 alleles were analysed in patients with multiple sclerosis (MS) with onset over 50years of age and compared with 100 patients with early onset MS (EOMS). Of a cohort of 829 patients with MS, 73 (8.8%) presented at over 50years of age, including 14 (1.7%) over 60years… CONTINUE READING