Clinical presentation and therapeutic outcome in 26 patients with primary CNS lymphoma.

@article{Herrlinger1998ClinicalPA,
  title={Clinical presentation and therapeutic outcome in 26 patients with primary CNS lymphoma.},
  author={Ulrich Herrlinger and Martin Schabet and Michael Clemens and Rolf Dieter Kortmann and Dirk Petersen and Bernd E. Will and Richard Meyermann and Johannes Dichgans},
  journal={Acta neurologica Scandinavica},
  year={1998},
  volume={97 4},
  pages={257-64}
}
This retrospective study analyzes clinical features and therapeutic outcome in 26 immunocompetent patients with primary central nervous system lymphoma (PCNSL). Most patients presented with personality changes. PCNSL lesions were mainly iso- or hyperdense, enhancing lesions on CT scan, hypointensive on T1-, and hyperintensive on T2-weighted MRI. Multiple lesions were found in about 60% of patients. Nine of 11 patients receiving radiotherapy alone showed complete remission (CR). Median survival… CONTINUE READING