Clinical pilot study on high-dose intraarterial chemotherapy with direct hemoperfusion under hepatic venous isolation in patients with advanced hepatocellular carcinoma.

@article{Ku1995ClinicalPS,
  title={Clinical pilot study on high-dose intraarterial chemotherapy with direct hemoperfusion under hepatic venous isolation in patients with advanced hepatocellular carcinoma.},
  author={Yonson Ku and Takumi Fukumoto and Takeshi Iwasaki and Masahiro Tominaga and Masahiro Samizo and Takeo Nishida and Yoshikazu Kuroda and Shozo Hirota and Minako Sako and Hidefumi Obara},
  journal={Surgery},
  year={1995},
  volume={117 5},
  pages={510-9}
}
BACKGROUND We recently developed a novel system of direct hemoperfusion under hepatic venous isolation in an attempt to achieve high-dose intraarterial chemotherapy for patients with malignant liver tumors. We report here the results of treatment of these patients with advanced hepatocellular carcinoma. METHODS Adriamycin (100 to 150 mg/m2) was administered into the hepatic artery of 15 patients, under conditions of extracorporeal drug elimination by direct hemoperfusion under hepatic venous… CONTINUE READING

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