Clinical picture and treatment of 2212 patients with common variable immunodeficiency.

  title={Clinical picture and treatment of 2212 patients with common variable immunodeficiency.},
  author={B. Gathmann and Nizar Mahlaoui and Laurence G{\'e}rard and Eric Oksenhendler and Klaus Warnatz and Ilka Schulze and G. Kindle and Taco Willem Kuijpers and Rachel T van Beem and David S-M. Guzman and Sarita Workman and Pere Soler-Palac{\'i}n and Javier de Gracia and Torsten Witte and Reinhold Ernst Schmidt and Jiř{\'i} Litzman and Eva Hlav{\'a}{\vc}kov{\'a} and V Thon and Michael Borte and Stephan Borte and Dinakantha Kumararatne and Conleth Feighery and Hilary Longhurst and Matthew R Helbert and Anna Szaflarska and Anna {\vS}ediv{\'a} and Bernd H. Belohradsky and Alison M. Jones and Ulrich Baumann and Isabelle Meyts and Necil Kutukculer and Per W{\aa}gstr{\"o}m and Nermeen Mouftah Galal and Joachim Roesler and Evangelia Farmaki and Natalia A. Zinovieva and Peter {\vC}i{\vz}n{\'a}r and Efimia Papadopoulou-Alataki and Kirsten Bienemann and Sirje Velbri and Zoya Panahloo and Bodo Grimbacher},
  journal={The Journal of allergy and clinical immunology},
  volume={134 1},
BACKGROUND Common variable immunodeficiency (CVID) is an antibody deficiency with an equal sex distribution and a high variability in clinical presentation. The main features include respiratory tract infections and their associated complications, enteropathy, autoimmunity, and lymphoproliferative disorders. OBJECTIVE This study analyzes the clinical presentation, association between clinical features, and differences and effects of immunoglobulin treatment in Europe. METHODS Data on 2212… CONTINUE READING