Clinical phenotypes associated with DISC1, a candidate gene for schizophrenia

@article{Blackwood2009ClinicalPA,
  title={Clinical phenotypes associated with DISC1, a candidate gene for schizophrenia},
  author={Douglas H.R. Blackwood and Walter J. Muir},
  journal={Neurotoxicity Research},
  year={2009},
  volume={6},
  pages={35-41}
}
Genetic factors play an important part in the development of schizophrenia and bipolar disorder, and linkage analyses in families have successfully identified several chromosomal regions containing candidate genes. A single large pedigree has been described in which schizophrenia and depression segregate with a balanced chromosomal translocation involving the long arm of chromosome 1 and the short arm of chromosome 11. The gene named DISC1, disrupted at the chromosome 1 breakpoint, is a novel… Expand
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