Clinical pharmacology of topiramate: a review.

@article{Garnett2000ClinicalPO,
  title={Clinical pharmacology of topiramate: a review.},
  author={William R. Garnett},
  journal={Epilepsia},
  year={2000},
  volume={41 Suppl 1},
  pages={S61-5}
}
Clinical success with an antiepileptic drug (AED) depends primarily on its efficacy and tolerability. Clinicians also need to have a basic understanding of an AED's pharmacokinetic characteristics, particularly those affecting the potential for drug interactions such as hepatic enzyme inhibition or induction and protein-binding displacement. Successful treatment may be complicated by pharmacokinetic characteristics such as a short half-life, nonlinear kinetics, and active metabolites… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 32 extracted citations

Similar Papers

Loading similar papers…