Clinical pharmacokinetics of vancomycin.

  title={Clinical pharmacokinetics of vancomycin.},
  author={Gary R. Matzke and George G Zhanel and David R. P. Guay},
  journal={Clinical pharmacokinetics},
  volume={11 4},
Vancomycin utilisation has increased dramatically in the last 10 years due to the increasing clinical significance of infections with methicillin-resistant staphylococci. Recent studies have focused on characterising the disposition of vancomycin in patients and assessing the relationship between serum concentrations and therapeutic as well as adverse effects. Although vancomycin is not appreciably absorbed from the intact gastrointestinal tract, several recent case reports have documented the… CONTINUE READING
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