Clinical pharmacokinetics of tacrolimus after the first oral administration in combination with mycophenolate mofetil and prednisone in Chinese renal transplant recipients.

@article{Chen2005ClinicalPO,
  title={Clinical pharmacokinetics of tacrolimus after the first oral administration in combination with mycophenolate mofetil and prednisone in Chinese renal transplant recipients.},
  author={Y H Chen and K-L. Zheng and L Chen and Yanmei Dai and J G Fei and Jiang Qiu and Jin Li},
  journal={Transplantation proceedings},
  year={2005},
  volume={37 10},
  pages={4246-50}
}
INTRODUCTION Data on tacrolimus pharmacokinetics in combination with mycophenolate mofetil and prednisone are scarce in Chinese renal transplantation recipients. The purpose of this study was to detect interpatient pharmacokinetic variability of tacrolimus and to assess the predictability of individual tacrolimus concentrations at various times for the area under the curve (AUC) seeking to find the best sampling time for an abbreviated AUC to predict the total body exposure of tacrolimus after… CONTINUE READING