Clinical pharmacokinetics of amiodarone.

@article{Latini1984ClinicalPO,
  title={Clinical pharmacokinetics of amiodarone.},
  author={Roberto Latini and Gianni Tognoni and Robert E. Kates},
  journal={Clinical pharmacokinetics},
  year={1984},
  volume={9 2},
  pages={136-56}
}
Amiodarone is an iodinated benzofuran derivative with recognised antiarrhythmic activity in man. As yet, its pharmacokinetic behaviour has not been satisfactorily characterised. Specific and sensitive high-pressure liquid chromatographic methods have become available only recently and this partly explains the scarcity of pharmacokinetic data on the drug. Available evidence suggests that absorption of amiodarone following oral administration is erratic and unpredictable; oral bioavailability… CONTINUE READING

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