Clinical pharmacokinetics in pregnancy and perinatology. II. Penicillins.

@article{Nau1987ClinicalPI,
  title={Clinical pharmacokinetics in pregnancy and perinatology. II. Penicillins.},
  author={Heinz Nau},
  journal={Developmental pharmacology and therapeutics},
  year={1987},
  volume={10 3},
  pages={174-98}
}
  • Heinz Nau
  • Published 1987 in Developmental pharmacology and therapeutics
Ampicillin has been most thoroughly studied in regard to placental transfer. Both during the first/second trimester and at term, fetal drug levels rose slowly to reach values similar to those in the maternal circulation 1-3 h after maternal drug administration; thereafter, fetal drug levels exceeded corresponding maternal values. Amniotic fluid levels were… CONTINUE READING