Clinical pharmacokinetics and pharmacodynamics of ganciclovir and valganciclovir in children with cytomegalovirus infection.

INTRODUCTION Among infants and immunocompromised children cytomegalovirus (CMV) is associated with significant morbidity and mortality. AREAS COVERED This review describes the clinical pharmacokinetics and pharmacodynamics of ganciclovir and valganciclovir for the treatment and prevention of CMV infection in children. EXPERT OPINION A 24-h ganciclovir… CONTINUE READING