Clinical outcomes with unfractionated heparin or low-molecular-weight heparin as bridging therapy in patients on long-term oral anticoagulants: the REGIMEN registry.

@article{Spyropoulos2006ClinicalOW,
  title={Clinical outcomes with unfractionated heparin or low-molecular-weight heparin as bridging therapy in patients on long-term oral anticoagulants: the REGIMEN registry.},
  author={Alex C. Spyropoulos and Alexander G. G. Turpie and Andrew S. Dunn and John M. Spandorfer and James Demetrios Douketis and A. W. Jacobson and Floyd J. Frost},
  journal={Journal of thrombosis and haemostasis : JTH},
  year={2006},
  volume={4 6},
  pages={1246-52}
}
BACKGROUND Patients who receive long-term oral anticoagulant (OAC) therapy often require interruption of OAC for an elective surgical or an invasive procedure. Heparin bridging therapy has been used in these situations, although the optimal method has not been established. No large prospective studies have compared unfractionated heparin (UFH) with low-molecular-weight heparin (LMWH) for the perioperative management of patients at risk of thromboembolism requiring temporary interruption of long… CONTINUE READING
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