Clinical outcomes of xeno-free expansion and transplantation of autologous ocular surface epithelial stem cells via contact lens delivery: a prospective case series

@inproceedings{Bobba2015ClinicalOO,
  title={Clinical outcomes of xeno-free expansion and transplantation of autologous ocular surface epithelial stem cells via contact lens delivery: a prospective case series},
  author={Samantha Bobba and Sharron Chow and Stephanie Watson and Nick Di Girolamo},
  booktitle={Stem Cell Research & Therapy},
  year={2015}
}
Depletion of limbal stem cells leads to a debilitating condition known as limbal stem cell deficiency, characterised by impaired corneal wound healing and poor vision. The aim of this study was to determine whether delivering progenitor cells on a contact lens is a viable and effective alternative to current transplantation techniques, which are complicated by biological and xenogeneic materials. Sixteen eyes of 16 patients who had total (n = 14) and partial (n = 2) limbal stem cell deficiency… CONTINUE READING
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