Clinical outcomes in 21-hydroxylase deficiency

@article{Nordenstrm2021ClinicalOI,
  title={Clinical outcomes in 21-hydroxylase deficiency},
  author={Anna Nordenstr{\"o}m and Svetlana Lajic and Henrik Falhammar},
  journal={Current Opinion in Endocrinology \& Diabetes and Obesity},
  year={2021},
  volume={28},
  pages={318 - 324}
}
Purpose of review The introduction of synthetic glucocorticoids 70 years ago made survival possible in classic 21-hydroxylase deficiency (21OHD). The currently used glucocorticoid therapy may lead to unphysiological dosing with negative consequencies on health in addition to the problems that may arise due to androgen over-exposure. Recent findings Fertility in females with 21OHD seemed to be impaired, especially in the salt-wasting (SW) phenotype but when pregnancies did occur there was a… 
Review Article Long-Term Outcomes of Congenital Adrenal Hyperplasia
TLDR
The different long-term outcomes of CAH are discussed, including elevated steroid precursor and adrenocorticotropic hormone levels, living with a congenital condition as well as the proximity of the cytochrome P450 family 21 subfamily A member 2 ( CYP21A2 ) gene to other genes.
Adrenal myelolipomas.

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