Clinical outcomes from bilateral versus unilateral stimulation of the pedunculopontine nucleus with and without concomitant caudal zona incerta region stimulation in Parkinson's disease.

@article{Khan2012ClinicalOF,
  title={Clinical outcomes from bilateral versus unilateral stimulation of the pedunculopontine nucleus with and without concomitant caudal zona incerta region stimulation in Parkinson's disease.},
  author={Sadaquate Khan and Shazia Javed and Lucy K. Mooney and Paul White and Puneet Plaha and Alan L. Whone and Steven S Gill},
  journal={British journal of neurosurgery},
  year={2012},
  volume={26 5},
  pages={722-5}
}
INTRODUCTION The Pedunculopontine nucleus is a novel target for deep brain stimulation and this may improve postural instability and gait dysfunction in Parkinson's disease. If unilateral Pedunculopontine nucleus stimulation is as efficacious as bilateral stimulation this would lead to less surgical risk. METHODS 5 Parkinson's disease patients with bilateral caudal Zona Incerta region and Pedunculopontine nucleus electrodes were assessed using the motor component of the Unified Parkinson's… CONTINUE READING