Clinical outcomes following treatment of human intrabony defects with GTR/bone replacement material or access flap alone. A multicenter randomized controlled clinical trial.

@article{Tonetti2004ClinicalOF,
  title={Clinical outcomes following treatment of human intrabony defects with GTR/bone replacement material or access flap alone. A multicenter randomized controlled clinical trial.},
  author={Maurizio S Tonetti and Pierpaolo Cortellini and Niklaus P Lang and Jean E. Suvan and Patrick Adriaens and Dominik Dubravec and Alberto Fonzar and Ioannis Fourmousis and Giulio Rasperini and Roberto Rossi and Maurizio Silvestri and Heinz Topoll and Beat Wallkamm and Michael Zybutz},
  journal={Journal of clinical periodontology},
  year={2004},
  volume={31 9},
  pages={770-6}
}
AIM This prospective multicenter randomized controlled clinical trial was designed to compare the clinical outcomes of papilla preservation flap surgery with or without the application of a guided tissue regeneration (GTR)/bone replacement material. MATERIALS AND METHODS One hundred and twenty-four patients with advanced chronic periodontitis were recruited in 10 centers in seven countries. All patients had at least one intrabony defect of > or = 3 mm. The surgical procedures included access… CONTINUE READING

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