Clinical outcome of isolated serous tubal intraepithelial carcinomas (STIC).

  title={Clinical outcome of isolated serous tubal intraepithelial carcinomas (STIC).},
  author={Stephanie L. Wethington and Kay J Park and Robert A Soslow and Noah D. Kauff and Carol Leslie Brown and Fanny Dao and Ebunoluwa Otegbeye and Yukio Sonoda and Nadeem R. Abu-Rustum and Richard R. Barakat and Douglas A. Levine and Ginger J. Gardner},
  journal={International journal of gynecological cancer : official journal of the International Gynecological Cancer Society},
  volume={23 9},
OBJECTIVE Risk-reducing salpingo-oophorectomy (RRSO) is recommended for women with BRCA mutation due to increased risk of pelvic serous carcinoma. Serous tubal intraepithelial carcinoma (STIC) is a pathologic finding of unknown clinical significance. This study evaluates the clinical outcome of patients with isolated STIC. MATERIALS/METHODS We retrospectively reviewed the medical records of consecutive patients with a germline BRCA1/2 mutation or a high-risk personal or family history of… CONTINUE READING