Clinical outcome of individualised treatment of multidrug-resistant tuberculosis in Latvia: a retrospective cohort study

@article{Leimane2005ClinicalOO,
  title={Clinical outcome of individualised treatment of multidrug-resistant tuberculosis in Latvia: a retrospective cohort study},
  author={Vaira Leimane and Vija Riekstiņa and Timothy H. Holtz and Evija Zarovska and Vija Skripconoka and Lorna E. Thorpe and Kayla F. Laserson and Charles D. Wells},
  journal={The Lancet},
  year={2005},
  volume={365},
  pages={318-326}
}

Baseline Predictors of Treatment Outcomes in Children With Multidrug-Resistant Tuberculosis: A Retrospective Cohort Study.

  • S. ChiangJ. Starke M. Becerra
  • Medicine
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2016
TLDR
High cure rates can be achieved in children with MDR tuberculosis using tailored regimens containing second-line drugs, however, children faced significantly higher risk of death or treatment failure if they had severe disease or were underweight.

Treatment outcome of multi-drug resistant tuberculosis in the United Kingdom: retrospective-prospective cohort study from 2004 to 2007.

  • L. AndersonS. Tamne I. Abubakar
  • Medicine
    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
  • 2013
TLDR
The findings support current World Health Organization (WHO) guidelines for MDR-TB treatment and suggest the UK should consider adopting individualised regimens based on WHO recommended drugs, taking into account drug sensitivities.

Treatment outcome of multidrug/extensively drug-resistant tuberculosis in Latvia, 2000–2004

TLDR
Overall, treatment success among all MDR-TB cases increased over time, and risk factors for poor outcome in a high-prevalence country that screens all TB patients for first-line anti-TB drug resistance were assessed.

Prognostic factors of treatment among patients with multidrug-resistant tuberculosis in Egypt.

Treatment outcomes for HIV-uninfected patients with multidrug-resistant and extensively drug-resistant tuberculosis.

  • Yong-Soo KwonY. Kim W. Koh
  • Medicine
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2008
TLDR
Early aggressive treatment comprising at least 4 effective drugs and surgical resection, when indicated, may improve the outcome for patients with MDR TB or XDR TB.

Treatment outcome of multidrug-resistant tuberculosis with modified DOTS-plus strategy: A 2 years' experience

TLDR
MDR-TB can be cured successfully with modified DOTS-Plus strategy and requires much effort from both the patients and health-care workers and can be an alternative model for treating MDR- TB patients in private sector.

University of Groningen Multidrug Resistant Pulmonary Tuberculosis Treatment Regimens and Patient Outcomes

TLDR
In this individual patient data meta-analysis of observational data, improved MDR-TB treatment success and survival were associated with use of certain fluoroquinolones, ethionamide, or prothionamide and greater total number of effective drugs.
...

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