Clinical outcome of frequent exposure to Torque Teno virus (TTV) through blood transfusion in thalassemia patients with or without hepatitis C virus (HCV) infection.

@article{Hu2008ClinicalOO,
  title={Clinical outcome of frequent exposure to Torque Teno virus (TTV) through blood transfusion in thalassemia patients with or without hepatitis C virus (HCV) infection.},
  author={Y W Hu and Moslih I Al-Moslih and Mahmoud Talib Al Ali and Samra Uzicanin and Heather Perkins and Qi-long Yi and Shabnam Rahimi Khameneh and Jun Wu and Earl G. Brown},
  journal={Journal of medical virology},
  year={2008},
  volume={80 2},
  pages={365-71}
}
As a consequence of the high prevalence of TorqueTeno virus (TTV) in blood donors, thalassemia patients frequently acquire various genotypes of this virus through therapeutic blood transfusions. At present, the clinical consequences of TTV infection remain indeterminate for these patients. Here, several hundred thalassemia patients were tested for the presence of TTV and its genotypes using a combination of PCR and clone-based DNA sequencing. Approximately 10% (12/118) of the patients aged 2-20… CONTINUE READING