Clinical outcome and olanzapine plasma levels in acute schizophrenia.

  title={Clinical outcome and olanzapine plasma levels in acute schizophrenia.},
  author={Massimo Carlo Mauri and C P C Steinhilber and Raffaella A. Marino and Emanuele Invernizzi and Alessio Fiorentini and Giancarlo Cerveri and Maria Luisa Baldi and Francesco Barale},
  journal={European psychiatry : the journal of the Association of European Psychiatrists},
  volume={20 1},
PURPOSE This open label study was performed to evaluate the relationship between the plasma concentration of olanzapine and the response in acute schizophrenic inpatients. MATERIAL AND METHODS A total of 54 inpatients, 38 males and 16 females, age ranging from 18 to 75 years, affected by Schizophrenia (DSM IV criteria) during an exacerbation phase were included in the study. Olanzapine (OLZ) was started at a dose of 5-20 mg/day and was increased to a mean dose of 15.27 mg +/-5.53 S.D… CONTINUE READING

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