Clinical measures of islet function: usefulness to characterize defects in diabetes.

@article{Ahrn2008ClinicalMO,
  title={Clinical measures of islet function: usefulness to characterize defects in diabetes.},
  author={Bo Ahr{\'e}n and Richard E. Pratley and Mazin Soubt and Beth Elaine Dunning and James E Foley},
  journal={Current diabetes reviews},
  year={2008},
  volume={4 2},
  pages={129-45}
}
In healthy individuals, the ability of the pancreatic islets to sense and respond appropriately to changes in plasma glucose levels maintains plasma glucose levels within a narrow range despite broad fluctuations in nutrient intake and variable "demand" for insulin imposed by changes in insulin sensitivity. This ability of the pancreatic islets is lost in… CONTINUE READING