Clinical meaningfulness of complete skin clearance in psoriasis.

  title={Clinical meaningfulness of complete skin clearance in psoriasis.},
  author={B E Strober and Kim Papp and Mark G. Lebwohl and K Reich and C Paul and Andrew Blauvelt and Kenneth B. Gordon and Cassandra E Milmont and Hema N. Viswanathan and Joanne Li and Lionel Pinto and David J. Harrison and Greg Kricorian and Ajay Nirula and Paul A Klekotka},
  journal={Journal of the American Academy of Dermatology},
  volume={75 1},
BACKGROUND New psoriasis therapies have increased the ability to achieve skin clearance. However, insufficient evidence exists on the impact of total skin clearance from the patient perspective. OBJECTIVE We sought to determine if complete skin clearance is clinically meaningful compared with treatment responses without clearance. METHODS Pooled data from 3 phase-III trials were used to compare results for patients with complete skin clearance (Psoriasis Area and Severity Index [PASI] 100… CONTINUE READING
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