Clinical manifestations of cerebral amyloid angiopathy-related inflammation.

  title={Clinical manifestations of cerebral amyloid angiopathy-related inflammation.},
  author={Jessica A Eng and Matthew P. Frosch and Kyungchan Choi and George William Rebeck and Steven A. Greenberg},
  journal={Annals of neurology},
  volume={55 2},
To explore the clinical effects of inflammation associated with vascular deposits of the amyloid beta peptide (A beta), we analyzed 42 consecutive patients with pathologically diagnosed cerebral amyloid angiopathy (CAA) for evidence of an inflammatory response. Inflammation with giant-cell reaction surrounding amyloid-laden vessels was identified in 7 of the 42 cases. The clinical symptoms in each of the seven were subacute cognitive decline or seizure rather than hemorrhagic stroke, the… CONTINUE READING
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