Clinical manifestations of IgE hypogammaglobulinemia.

  title={Clinical manifestations of IgE hypogammaglobulinemia.},
  author={J Kelly Smith and Guha Krishnaswamy and Rachel Dykes and Stasia Reynolds and Steven L. Berk},
  journal={Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology},
  volume={78 3},
BACKGROUND Although IgE has been shown to play a role in the expulsion of intestinal parasites in experimental animals, its overall contribution to host defense in humans remains a subject of controversy. In order to clarify the potential role of IgE in host defense, we have studied the clinical characteristics of patient with serum IgE levels of < 2.5 IU/mL, using patients with normal or elevated IgE levels as controls. OBJECTIVE To determine the clinical characteristics of IgE deficiency… CONTINUE READING