Clinical management of primary central nervous system germ cell tumors.

@article{Matsutani2004ClinicalMO,
  title={Clinical management of primary central nervous system germ cell tumors.},
  author={Masao Matsutani},
  journal={Seminars in oncology},
  year={2004},
  volume={31 5},
  pages={676-83}
}
Despite excellent long-term results for patients with germinoma treated with radiation therapy, the potential for late effects makes the treatment controversial. On the other hand, most patients with non-germinomatous tumors treated by conventional treatment with surgery and radiation therapy fail to survive longer than 3 years. After combination chemotherapy with cisplatin was confirmed to be effective in gonadal germ cell tumors, germ cell tumors of the brain became candidates for… CONTINUE READING