Clinical isolates of uropathogenic Escherichia coli ST131 producing NDM-7 metallo-β-lactamase in China.

@article{Wang2016ClinicalIO,
  title={Clinical isolates of uropathogenic Escherichia coli ST131 producing NDM-7 metallo-β-lactamase in China.},
  author={Lianhui Wang and Pan-Pan Liu and Dan-dan Wei and Yang Liu and La-Gen Wan and Tian-xin Xiang and Yu-Juan Zhang},
  journal={International journal of antimicrobial agents},
  year={2016},
  volume={48 1},
  pages={
          41-45
        }
}
Here we report five cases of NDM-7-producing Escherichia coli from patients with bacteriuria in a teaching hospital in mainland China. Two isolates belonged to sequence type 131 (ST131), simultaneously carrying blaCTX-M-15, blaSHV-11, blaTEM-1 and qnrS1. The blaNDM-7 gene was located on a conjugative IncX3-type plasmid bearing blaTEM-1 and qnrS1. These findings indicate the spread of NDM-7 metallo-β-lactamase in a highly resistant and virulent E. coli sequence type in China. 
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