Clinical involvement in daughters of men with fragile X-associated tremor ataxia syndrome.

@article{Chonchaiya2010ClinicalII,
  title={Clinical involvement in daughters of men with fragile X-associated tremor ataxia syndrome.},
  author={Weerasak Chonchaiya and Danh V. Nguyen and Jessica L Au and Luis Caro Campos and Elizabeth M. Berry-Kravis and K Lohse and Yi Mu and Agustini Utari and Crystal Hervey and L Wang and P. F. Sorensen and Kylee R Cook and Louise W. Gane and Flora Tassone and Randi J. Hagerman},
  journal={Clinical genetics},
  year={2010},
  volume={78 1},
  pages={38-46}
}
Women with the fragile X mental retardation 1 (FMR1) premutation often have concerns about neurological and medical problems, as they become older and if their fathers experience fragile X-associated tremor/ataxia syndrome (FXTAS). We therefore determined the prevalence of these problems in 110 daughters of men with FXTAS [mean age of 44.8 years (SD 8.2)]. We compared them with 43 female controls with normal FMR1 alleles [mean age of 43.8 years (SD 8.1)] and 36 premutation carrier daughters of… CONTINUE READING