Clinical investigation of the analgesic potency and respiratory depressant activity of fentanyl, a new narcotic analgesic.

Abstract

A controlled clinical comparison of fentanyl and morphine in 75 postsurgical patients is presented. In addition, the ability of the two drugs to produce respiratory depression was determined in six healthy volunteers. The results of these studies indicate that 0.2 mg. fentanyl intramuscularly is equianalgesic with 10 mg. morphine intramuscularly, and it would appear that there is no advantage in the use of fentanyl for the relief of postsurgical pain.

Cite this paper

@article{Finch1967ClinicalIO, title={Clinical investigation of the analgesic potency and respiratory depressant activity of fentanyl, a new narcotic analgesic.}, author={Joanne S Finch and T J Dekornfeld}, journal={The Journal of clinical pharmacology and the journal of new drugs}, year={1967}, volume={7 1}, pages={46-51} }