Clinical improvement precedes lesion size regression in a severe case of acute disseminated encephalomyelitis.

Abstract

Here, we present a case of a severe acute disseminated encephalomyelitis (ADEM) of a 42-year-old male patient. The diagnosis was established after brain biopsy and due to acutely evolving encephalopathy occurring in the context of atypical Mycoplasma pneumoniae (MP). We analysed the prominent MRI white matter lesions using a three-dimensional algorithm as cutting-edge technique to study morphological abnormalities and correlated them to the clinical condition of the patient. We found a discrepancy between the lesion size and the clinical deficits of the patient, actually the clinical improvement antedated the regression of the white matter lesions.

DOI: 10.1136/bcr-2012-006844

Cite this paper

@article{Stettner2012ClinicalIP, title={Clinical improvement precedes lesion size regression in a severe case of acute disseminated encephalomyelitis.}, author={Mark Stettner and Philipp Albrecht and Angelika Derksen and C. J. Hartmann and Bernd Turowski and Eva Neuen-Jacob and Hans - Peter Hartung and Bernd C. Kieseier and Gabriele Arendt}, journal={BMJ case reports}, year={2012}, volume={2012} }