Clinical importance of the cytochromes P450.


The human cytochrome P450 (CYP) superfamily comprises 57 genes. These genes code for enzymes that can have a role in: metabolism of drugs, foreign chemicals, arachidonic acid and eicosanoids; cholesterol metabolism and bile-acid biosynthesis; steroid synthesis and metabolism; vitamin D(3) synthesis and metabolism; retinoic acid hydroxylation; and those of… (More)


Cite this paper

@article{Nebert2002ClinicalIO, title={Clinical importance of the cytochromes P450.}, author={D. Nebert and David W. Russell}, journal={Lancet}, year={2002}, volume={360 9340}, pages={1155-62} }