Clinical importance of myeloid-antigen expression in acute lymphoblastic leukemia of childhood.

@article{Wiersma1991ClinicalIO,
  title={Clinical importance of myeloid-antigen expression in acute lymphoblastic leukemia of childhood.},
  author={Susan R. Wiersma and J. Ortega and Esther Sobel and Kenneth I. Weinberg},
  journal={The New England journal of medicine},
  year={1991},
  volume={324 12},
  pages={800-8}
}
BACKGROUND Leukemic cells in 15 to 25 percent of patients with acute lymphoblastic leukemia (ALL) express myeloid antigens as well as lymphoid antigens (the latter reflecting B-cell or T-cell lineage). The relations of myeloid-antigen expression to other features of ALL and to prognosis have been controversial. METHODS We analyzed clinical and laboratory features present at diagnosis in 236 consecutive cases of ALL in children. Immunophenotyping, including single- and dual-fluorescence… CONTINUE READING

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