Clinical importance of inter-episode symptoms in patients with bipolar affective disorder.

@article{Morriss2002ClinicalIO,
  title={Clinical importance of inter-episode symptoms in patients with bipolar affective disorder.},
  author={Richard K Morriss},
  journal={Journal of affective disorders},
  year={2002},
  volume={72 Suppl 1},
  pages={S3-13}
}
A literature review was performed to determine whether inter-episode symptoms are of clinical importance in the management of bipolar disorder. Inter-episode symptoms are easy to miss but observational studies confirm that they are related to impaired function and reduced survival to full relapse. Randomised, controlled trials with lithium carbonate, and two studies exploring psychological treatments to recognise and treat prodromal symptoms of manic or depressive relapse, suggest some inter… CONTINUE READING