Clinical implications of sperm DNA damage.

  title={Clinical implications of sperm DNA damage.},
  author={Sheena E. M. Lewis and Luke Simon},
  journal={Human fertility},
  volume={13 4},
Traditionally, the diagnosis of male infertility has relied upon microscopic assessment and biochemical assays to determine human semen quality. These tests are essential to provide the fundamental information on which clinicians base their initial diagnosis. However, none of these parameters addresses sperm function and their clinical value in predicting fertility is questionable. The advent of intracytoplasmic sperm injection (ICSI) has further reduced the significance and perceived need for… CONTINUE READING


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