Clinical implications of progressive transformation of germinal centers.

@article{Osborne1984ClinicalIO,
  title={Clinical implications of progressive transformation of germinal centers.},
  author={Becky Osborne and James J. Butler},
  journal={The American journal of surgical pathology},
  year={1984},
  volume={8 10},
  pages={725-33}
}
Fifty patients whose lymph node biopsies showed reactive follicular hyperplasia with the presence of progressive transformation of germinal centers were evaluated for current status of health, prior or subsequent development of Hodgkin's disease, and etiology of the lymph node hyperplasia. Histologically, on a background of reactive follicular hyperplasia, the nodes contained one or more germinal centers showing progressive transformation. These were three to four times the diameter of the… CONTINUE READING

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